Anonymous Key Generation Technique with Contributory Broadcast Encryption

Encryption is used in a communication system to secure information in the transmitted messages from anyone other than the well-intended receiver. To perform the encryption and decryption the transmitter and receiver should have matching encryption and decryption keys. For sending safeguard information to group needed broadcast encryption (BE). BE allows a sender to securely broadcast to any subset of members and require a trusted party to distribute decryption keys. Group key agreement (GKA) protocol allows a number of users to establish a common secret channel via open networks. Observing that a major goal of GKA for most applications is to create a confidential channel among group members, but a sender cannot omit any particular member from decrypting the cipher texts. By bridging BE and GKA notion with a hybrid primitive referred to as contributory broadcast encryption (CBE). With these primitives, a group of members move through a common public encryption key while each member having there decryption key. A sender seeing the public group encryption key can limit the decryption to subset of members of sender’s choice. A simple way to generate these keys is to use the public key distribution system invented by Diffie and Hellman. That system, however, pass only one pair of communication stations to share a particular pair of encryption and decryption keys. Key distribution sets are used to generate keys and Elliptic Curve Cryptography (ECC) is used for the encryption and decryption of documents; and this going to provide the security for the documents over group communication

Immunohistochemical and Molecular Detection of pH1N1 in NecropsiedPulmonary Tissues of Fatal Cases with Indeterminate Conventional Testing

The rapid emergence of a novel influenza A/H1N1 virus designated pH1N1 2009 caused one of the fastest pandemics of the twentieth century. The rapid development of an accurate detection test for this pandemic virus using reverse transcription-real time polymerase chain reaction (rRT-PCR) helped in timely diagnosis. In India this pandemic peaked between August to October 2009. The r-RT PCR for pH1N1 2009 was the main diagnostic test used on throat/nasopharyngeal swabs in all cases. While in majority of the cases this test provided reliable confirmation of the virus, it gave negative or indeterminate results in a subset of cases meeting the standard case definition for the pandemic infection and negative for seasonal flu. In the present study we examined 4 such fatal cases where microscopic pathology of the lung was consistent with viral bronchopneumonia for the presence of pH1N1 2009 using r-RT PCR on nucleic acid extracted from the paraffin sections that showed presence of viral antigens by immunohistochemistry. In all 4 cases pH1N1 sequences could be identified. These findings therefore emphasize the important role of microscopic pathology techniques in conjunction with molecular tools in the diagnostic confirmation of novel agents during a public health emergency

PROTECTIVE EFFECT OF DIOSGENIN AGAINST CARBON TETRACHLORIDE AND CISPLATIN INDUCED HEPATOTOXICITY IN RATS

Background: Activation of hepatic stellate cells (HSC) plays central role in the development of liver fibrosis. In HSC activation, the transforming growth factor-1 (TGF-1) is considered to be the main stimuli factor. Diosgenin are the steroidal saponin and found in Trigonella foenum graecum Linn (Fenugreek) and some other species of Dioscorea. Diosgenin attenuates HSC activation by inhibiting transforming growth factor. Aim: In present study an attempt was made to explore the effect of diosgenin on liver fibrosis. Methods: Liver fibrosis was induced in rats by carbon tetrachloride (CCl4) 1 ml/kg intraperitoneally twice a week for 28 days and cisplatin 3mg/kg intraperitoneally at 0, 1, 3 week for 4 weeks. The extent of liver fibrosis was assessed by measuring the weight of liver and levels of total bilirubin (TBL), hydroxyproline (HP) and serum enzymes due to deposition of extracellular matrix (ECM). Results: The administration of diosgenin reduced the liver weight of CCl4 and cisplatin treated animals and reduced the TBL, HP level and serum enzymes significantly and inhibited liver fibrosis induced by CCl4 and cisplatin. Conclusion: The result obtained in the present investigation, Diosgenin treatment exerted significant hepatoprotective effect in animals by inhibiting ECM deposition and HSCs activation

Detecting Malicious Applications from the cloud by using user feedback method

As in recent period of computers and internets, mobiles devices, Smartphone’s plays a vital role in human day to day activities. Also now a days Smartphone’s & tablets are becoming very popular especially android based Smartphone’s are gaining much more popularity as compared to Apple’s iOS. These Smartphone’s having lot of applications and features based on only internet but these new emerging features of these devices give opportunity to new malwares & threats. Android is comparatively new OS hence its makes very hard to detect and prevent these viruses and malwares attacks by using some basic traditional mechanisms. So security of these Smartphone’s is now becoming very popular issue of researchers. The lack of standard security mechanism in Android applications is very useful to hackers. So to overcome these various pitfalls we use cloud services as a security weapon for providing decent security system for Android applications

PROTECTIVE EFFECT OF DIOSGENIN AGAINST CARBON TETRACHLORIDE AND CISPLATIN INDUCED HEPATOTOXICITY IN RATS

Background: Activation of hepatic stellate cells (HSC) plays central role in the development of liver fibrosis. In HSC activation, the transforming growth factor-1 (TGF-1) is considered to be the main stimuli factor. Diosgenin are the steroidal saponin and found in Trigonella foenum graecum Linn (Fenugreek) and some other species of Dioscorea. Diosgenin attenuates HSC activation by inhibiting transforming growth factor. Aim: In present study an attempt was made to explore the effect of diosgenin on liver fibrosis. Methods: Liver fibrosis was induced in rats by carbon tetrachloride (CCl4) 1 ml/kg intraperitoneally twice a week for 28 days and cisplatin 3mg/kg intraperitoneally at 0, 1, 3 week for 4 weeks. The extent of liver fibrosis was assessed by measuring the weight of liver and levels of total bilirubin (TBL), hydroxyproline (HP) and serum enzymes due to deposition of extracellular matrix (ECM). Results: The administration of diosgenin reduced the liver weight of CCl4 and cisplatin treated animals and reduced the TBL, HP level and serum enzymes significantly and inhibited liver fibrosis induced by CCl4 and cisplatin. Conclusion: The result obtained in the present investigation, Diosgenin treatment exerted significant hepatoprotective effect in animals by inhibiting ECM deposition and HSCs activation

A Simple and Efficient Synthesis of 2,3-Diarylnaphthofurans using Sequential Hydroarylation/Heck Oxyarylation

An efficient and simnple strategy has been developed for the synthesis of 2,3-diarylnaphthofurans using sequential hydroarylation of naphthols and alkynes in the presence of In(OTf)3 under microwave irradiation followed by one-pot Heck-oxyarylation of generated 1-substituted-a-hydroxy styrenes

Transfer and Ensemble Approach for Breast Cancer Detection and Classification Using Deep Learning

Breast cancer is a serious disease that can cause significant health problems for women worldwide. It is crucial to detect and classify breast cancer early stage so that doctors can promptly treat it and aid patients in their recovery. Many investigators have used various deep learning (DL) strategies to detect and classify breast cancer. However, due to the complexity of the problem, relying on a single DL model may not suffice to achieve high accuracy. Therefore, this study suggests a transfer and ensemble deep model for breast cancer detection and classification. The suggested model involves using pre-trained models such as Sequential, Xception, DenseNet201, VGG16, and InceptionResNetV2. The top three models are selected to collaborate and deliver the most accurate results. The proposed DL model was tested on publicly available breast BUSI datasets, demonstrating its superiority over single DL models, achieving an accuracy of 87.9% on the BUSI dataset. Additionally, the model proved to be adapTABLE to different amounts of data, making it potentially valuable in hospitals and clinics

Effect of Polyamines on Storability and Quality of Pomegranate Fruit (Punica granatum L.) Cv. Bhagwa

Pomegranate cv. Bhagawa fruits harvested at adequate stage of maturity were dipped in aqueous solutions containing various concentrations of the polyamines putrescine (1mM, 2mM and 3mM) and spermidine (0.5mM, 1mM and 1.5mM), along with Tween-20 as a surfactant, for 5 minutes. The fruits were then stored at 5°C and 8°C temperature with under 90-95% relative humidity. Polyamine-treated fruits showed reduced chilling-injury, weight loss and respiration rate during storage at these 5°C and 8°C temperatures. An increasing trend in total soluble solids (TSS) content, and a decreasing trend in acidity were found in polyamine-treated fruits during storage at 5°C and 8°C temperature. Maximum reduction in chilling-injury was obtained with putrescine (2mM) at both the storage temperatures. Control fruits stored at 5°C and 8°C temperature rapidly developed chilling-injury developed symptoms of brown discoloration of skin and weight-loss in pomegranate fruits

Evaluation of Immunomodulatory activity of Diosgenin in rats

Background: The immune system is intrinsic to health. Modulation of the immune responses to alleviate the diseases by using herbal plants has been of interest for many years. Diosgenin, a naturally occurring steroid saponin mainly present in the seeds of fenugreek (Trigonella foenum graecum) and in the root tubers of wild yams (Dioscorea villosa). Activation of specific and nonspecific immunity results in stimulation of immune response. Diosgenin has the positive effects on both specific and nonspecific immunity. Aim: To study the immunomodulatory activity of Diosgenin in albino wistar rats. Method: The suspension of Diosgenin was given orally at the dosage level of 50, 100 and 150 mg/kg for 21 days in a rat. The immunomodulatory activity on specific and non-specific immunity was studied by heamagglutination antibody (HA) titer, delayed type hypersensitivity (DTH) response and carbon clearance test. Immunosuppression in a rat was induced by using Cyclophosphamide (100 mg/kg, p.o.). Sheep red blood cells (SRBCs) were used as antigen (0.1ml 20% SRBCs). Result: Diosgenin exhibited significant increase in the production of antibody titer in response to SRBC antigen. A significant increase in both primary and secondary HA titer was observed in immunosuppressed group treated with Diosgenin when compared with negative control. A significant increase in the DTH response was observed in immunosuppressed animals treated with Diosgenin, pre-sensitized with SRBCs antigen. Diosgenin exhibited significant increase in phagocytic index against control group, indicating the stimulation of the reticuloendothelial system. Conclusion: The study indicates that Diosgenin triggers stimulatory effect on specific and nonspecific immune response. The immunostimulant effect of Diosgenin could be attributed due to its saponin glycoside